Lyon, France
March 24th & 25th 2026
Hôpital Femme Mère Enfant (HFME)
This two-day educational programme has been designed to cover a range of important and topical areas in the field of alpha-mannosidosis (AM). The programme will comprise lecture-based teaching and discussions with the hospital's rare disease specialists.
Delegates will have the opportunity to observe and participate in patient case study discussion sessions, meet the multidisciplinary team, and learn how they work in a practical way to manage the care of their patients.
Learn from Lyon's leading rare disease specialists
Participate in case studies & MDT discussion
Hear the latest findings and Real World Evidence
The programme will address critical areas in alpha-mannosidosis management:
Collaborative MDT working on the AM patient journey
Current & emerging therapies for AM
Genetic testing, early recognition & newborn screening
Audiology, pulmonology, cardiology, orthopaedics & more
SPARKLE Registry & the role of prospective data
Diagnosis, overlaps & differential diagnosis
Physiotherapy, life-span care & outcomes
Psychological aspects & patient-centred management
Discuss compplex case studies with your fellow experts
Dr Nathalie Guffon is a Lyon-based paediatrician and metabolic specialist leading lysosomal disorder care at Hôpital Femme Mère Enfant (Hospices Civils de Lyon), with globally recognised expertise in alpha-mannosidosis and mucopolysaccharidoses (MPS).
Dr Guffon has been principal investigator and advisor on international studies and registries. She has shaped diagnostic pathways, enzyme replacement therapy, and real-world care standards, and is an active voice at global forums, championing integrated patient-centred care focused on early diagnosis, longitudinal follow-up, and quality of life.
Dr Nathalie Guffon
Collaborating as an MDT on the AM patient journey
Dr Nathalie Guffon
Dr Karla Cifuentes
Improving early recognition, Newborn Screening (NBS), and differential diagnosis for AM vs MPS
Magali Pettazzoni
Dr Nathalie Guffon / Dr Karla Cifuentes
Dr Nicolas Pangaud
Dr Pierre Journeau
Sara Cabet
Françoise Aubert
All Delegates
Dr Nathalie Guffon
Dr Sonia Ayari-Khalfallah
Dr Karla Cifuentes
Dr Nathalie Guffon / Dr Karla Cifuentes
Dr Nicolas Pianton
The role of patient registries, prospective & retrospective data
Dr Nathalie Guffon
Agathe Rizet
Discussion on challenges, psychosocial management, resources, patient pathways, referrals, communication, etc.
All Delegates
All Delegates
Spaces are limited for this Peer-to-Peer Exchange. Please register on the link below:
Register for the EventRegistration Password: Lyon2026
This is a non-promotional meeting organised by Pi Healthcare. For information about sponsorship, please see the Industry page.
Venue: Hôpital Femme Mère Enfant (HFME), Floor 10, Cardiology Building | Lyon, France